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SPECT-CT- technology of the future

INDIAN PATIENTS OF GASTROENTEROPANCREATIC NEUROENDOCRINE TUMOURS WITH LIVER METASTASIS TREATED WITH LUTHETIUM-177 DOTATATE THERAPY-RESPONSE PROFILE

SHEFALI GOKHALE
INLAKS AND BUDHRANI HOSPITAL,PUNE, INDIA


Introduction
Use of four treatment cycles of Luthetium-177 DOTATATE therapy in metastatic gastroenteropancreatic neuroendocrine tumours has shown survival benefit in some of them.
AIM
This is a prospective study to analyse the response profile in Indian patients of GEP NET with liver metastasis.
We report our findings on the following secondary end points:
  • Tumour regression
  • Symptom resolution

MATERIALS AND METHODS

TOTAL NUMBER OF PATIENTS: 11 MALES 9 FEMALES 2
AGE GROUP:41-71 YRS  

Inclusion criteria
  • not responding to long acting octreotide injections
  • the lesions were either too large or too many and hence could not be treated with radiofrequency ablation
  • tracer avid lesions on somatostatin receptor imaging
  • compromised liver reserve

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