Nuclear Medicine

The Department of Nuclear Medicine, M. N. Budhrani Cancer Institute is equipped with a SPECT-CT scanner, The Infinia Hawkeye 4 Nuclear system from GE Healthcare which is the latest in hybrid scanners (i.e CT & SPECT Dual Head Gamma Camera).

It provides fully registered functional (SPECT) and anatomical information in a single image with a single examination. This helps us to determine the nature and precise location of the lesion. Fusion images from complementary modalities offer a more complete and accurate assessment of the disease.

Thyroid Scan
Indications:

• Diffuse Goitre / Multinodular Goitre
• Autonomous toxic adenoma
• Toxic Goitre
• Thyroiditis
• Solitary nodular Goitre
• Thyroid cyst
• Iodine-131 Whole Body Scan in cases of differentiated carcinoma thyroid

Parathyroid Scan

• Parathyroid adenoma/ Parathyroid hyperplasia
• Ectopic location of parathyroid adenoma

SPECT – CT enable localization of retro thyroid, intra thyroid and other ectopic Parathyroid adenomas

Myocardial Perfusion Imaging / Stress Thallium
A normal stress MPI indicates a low risk (<1%) of developing any major event in the next 1 year irrespective of the risk factors- Journal of Nuclear Cardiology

• Screening for IHD
• Triple vessel disease, prior to CABG.
• To look for ischemia in symptomatic post angioplasty patients

SPECT – CT provides for attenuation and scatter correction and hence accurate interpretation of myocardial perfusion images.

Bone Scan

• Primary bone tumor
• Metastatic bone disease
• Fractures not detected by X-Ray
• Stress fracture v/s Shine splints
• Osteomyelitis v/s Cellulitis.
• Synovitis
• Avascular necrosis
• Metabolic bone diseases
• Pagets disease
• Fibrous dysplasia

Accurate localization by SPECT-CT helps differentiate benign from malignant lesions.

Renal Imaging (DTPA & DMSA Scan)

• Bilateral / unilateral hydronephrosis
• PUJ obstruction / VUJ obstruction.
• Rental artery steno sis (Pre and post captopril studies)
• Congenital malformations of kidneys – DMMSA scan (Horse-shoe kidney, duplex kidney, ectopic kidney)
• Acute / chronic pyelonephritis –for cortical scars (DMSA scan)
• Vesicouretic reflux
• In renal transplant patients –ATN rejection, urine leak , lymphocoele formation, screening for donor
• Direct radionuclide cystogram for determining vesicoureteric reflux (VUR)
• GFR by “Plasma sampling methode” – a gold standard method for determining GFR (We are the first centre in pune doing this test)

HIDA Scan

• Acute calculus / acalculus cholecystitis
• Chronic cholecystitis
• Sphincter of oddi dysfunction
• Calculation of Gall Bladder ejection fraction
• Duodenogastric reflux
• Bile leak
• Biliary atresia v/s Neonatal hepatitis

MIBI Brain SPECT

• To differentiate viable tumor tissue from radiation necrosis in postoperative, post radiotherapy patients of high grade gliomas

ECD Brain SPECT

• Detection of dementias
• Identifying epileptic focus
• Evalution of psychiatric disorders
• Assessment of stroke

Accurate functional information with anatomical localization by SPECT-CT plats
a major role in further management


Other Scans

• Dacryscintrigraphy- painless, simple and patient friendly method to evaluate obstruction in the lacrimal system
• Salivary gland scintigraphy
• GI Bleed studies
• Meckle’s Scan (to determine functioning ectopic gastic mucosa)
• GE Reflux Studies
• MUGA Scan
• Lung ventilation perfusion studies:to detect pulmonary thromboembolism , for quantification studies prior to therapy
• Lymphoscientigraphy: To grade lymphoedema and decide upon the mode of treatment:medical/ surgical

Other Oncology Scans

• Scintimammography
• Tc-99m DMSA (V)for staging of Medullary Thyroid Carcinoma
• Tc-99m tektrotyd scan for somatostatin receptor imaging
• I-131 MIBG Scan
• Lu-177 DOTATATE Scans for neuroendocrine tumors

Infection Imaging

• Labelled WBC Scans
• Gallium 67 Scans

Therapeutic Nuclear Medicine

• Iodine -131 treatment in case if Graves disease/ Toxic goiters/ AFTN
• Iodin-131 treatment in post operative cases of differentiated with carcinoma thyroid
• P-32/Sm -153 / Sr-89 palliative pain therapy in cancer patient with multiple bone metastasis
• I-131 MIBG therapy in neuroblastomas
• Radiation Synovectomy in patients with Rheumatoid arthritis
• We are recognized by BARC for giving Radioactive Iodine Treatment for Ca Thyroid Patients
• Luthetium-177 DOTATATE therapy for well differentiated neuroendocrine tumours- We are the first facility in Maharashtra, approved by BARC for this procedure.

New Scans/Procedures

• Dopamine Transporter Imaging Tc99m TRODAT Scans.(To differentiate essential tremors from early parkinson’s).
• Somatostatin receptor imaging: Tc-99m HYNICTOC and In-111 Octreotide Scans for neuroendocrine tumours.
• Radiation Synovectomy for painful joints.
• Palliative pain therapy in bone metastasis.
• Lu-177 DOTATATE therapy in Neuroendocrine tumours.
• Iodine-131 MIBG Therapy in paraganglioma, metastatic pheochromocytomas, neuroblastomas.

For further information and appointment,
Please contact: 020-66099862
(Monday to Saturday,9 am to 5:30 pm)